7 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Diuretic Sites of Action ... ) Loop agents (eg ... Diuretics #Sites #Action ... #nephrology #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Mechanisms of Action ... side effects (e.g ... #Metformin #Pharmacology ... diabetes #endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Mechanisms of Action ... GU infections (e.g ... #Summary #DM2 # ... diabetes #endocrinology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
mediated cytotoxic reaction ... , asthenia • Neurologic ... hyponatremia, rash, pruritus ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
Algorithm for the ... Evidence-Based Off-Label Pharmacologic ... nalfurafine 2.5 mcg ... uremia #itching #Algorithm ... Treatment #management #nephrology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Mechanisms of Action ... side effects (e.g ... #Summary #DM2 # ... diabetes #endocrinology
Pruritus Treatment Algorithm for Hemodialysis Patients 

Non-PharmacoIogicaI Measures 
 • Use gentle soap e.g. Dove
Pruritus Treatment ... Algorithm for Hemodialysis ... moisturizing cream (NOT lotion ... tolerated) #Pruritus ... #Treatment #Algorithm