15 results
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... side effects (e.g ... #Metformin #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Hyperglycemic Crisis - Algorithm ... criteria for DKA: • pH ... Hyperglycemic #Crisis #Algorithm ... #management #endocrinology ... #Diabetes #DM2
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... ) Loop agents (eg ... Adenosine #Nephron #Pathophysiology ... Sites #Action #nephrology ... #pharmacology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... GU infections (e.g ... SGLT2 #Inhibitors #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... side effects (e.g ... Receptor #Agonists #Pharmacology ... #Summary #DM2 # ... diabetes #endocrinology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
-5 inhibitors (e.g ... inflammation #BPH ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology ... #Urology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Differential Diagnosis Algorithm ... Hypertension - BP ... 90 (>130/80 for DM ... HTN #Secondary #Nephrology ... Differential #Diagnosis #Algorithm
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Differential Diagnosis Algorithm ... Pulmonary Disease Neurologic ... Myasthenia Gravis Pharmacologic ... • Drug Abuse (e.g ... Differential #Diagnosis #Algorithm
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
Algorithm for the ... Evidence-Based Off-Label Pharmacologic ... nalfurafine 2.5 mcg ... uremia #itching #Algorithm ... Treatment #management #nephrology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... hours or longer/BP ... Etiology: • Pathophysiology ... • EEG: With persistent ... diagnosis #management #neurology