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diagnosis management differential rheumatology comparison photo syndrome algorithm disorders rash treatment anemia blood classification dermatomyositis erythema erythematosus lupus pediatrics peds
Symptoms Distinguishing Groups of Cutaneous Drug Reactions IgE-mediated reactions: • Onset minutes to hours into treatment course
Distinguishing Groups of Cutaneous ... Raised off of the skin ... or severe cutaneous ... Blistering and/or skin ... #dermatology #clinical
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
Characteristic features of the rash are: -Rough texture (like sandpaper) -Worse in the skin folds e.g. groin, axilla,
-Worse in the skin ... folds e.g. groin ... Pastia’s lines) #Clinical ... #Dermatology #Peds
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... allergy, drug reaction ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Iron Deficiency (Eg ... Other • e.g ... HgbE, HgbC, etc. ... #Hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
Drug Reaction with ... Methylprednisolone 0.5 - 1.5 mg/kg ... cyclosporine, IVIG etc ... • Skin: topical ... Treatment #Management #dermatology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... altered colour e.g ... nipple-like mass e.g ... . e.g. psoriasis ... #Diagnosis #Dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... Autoimmune diseases (e.g ... disease: GI, neuro, cutaneous ... Malignancies (eg ... #differential #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
toxic aetiology: Skin ... of information (e.g ... for alternative causes ... vascular disorder (e.g ... Diagnosis #Algorithm #hepatology
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