23 results
Characteristic features of the rash are:

-Rough texture (like sandpaper)
-Worse in the skin folds e.g. groin, axilla,
-Worse in the skin ... folds e.g. groin ... Pastia’s lines) #Clinical ... #Dermatology #Peds
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... altered colour e.g ... bruise') is where bleeding ... . e.g. psoriasis ... #Diagnosis #Dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... epistaxis, gingival bleeding ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... #Workup #hematology
Embolic Phenomena: Purplish discoloration of skin resulting from embolus to small toe. In this case, the
discoloration of skin ... In this case, the ... #Dermatology #Septic ... Endocarditis #Janeway #Lesions ... #Photo #UCSDH
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
• Consistent bleeding ... normal in mild cases ... hemophilia type (e.g ... Avoid meds that ... Management #treatment #hematology
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
chemotherapy, etc ... possible malignancy (e.g ... pain, abnormal bleeding ... fracture or lyric lesion ... Electrophoresis #SPEP #Hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic ... pain Clinical ... Rule out other causes ... antiinflammatory properties e.g ... diagnosis #management #Dermatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
Helpful Clinical ... Drug history, e.g ... connective tissue, e.g ... #History #peds ... pediatrics #diagnosis #hematology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
fires, heating pads ... centrifugum • A chronic skin ... foods, stress, etc ... classic targetoid lesions ... differential #diagnosis #dermatology