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diagnosis management differential syndrome rheumatology treatment nephrology erythematosus hepatology lupus sclerosis sle systemic workup agammaglobulinemia algorithm alkaline alp als amyotrophic
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Lumbar Puncture, EEG ... #neurology #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
pylori test (GI symptoms ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... for secondary causes ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... brainstem syndromes (e.g ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... #symptoms #signs
Pisa Syndrome (pleurothotonus) on Physical Exam A tonic flexion of the trunk of the body to one
Caused commonly ... by: - drugs (e.g ... (eg Parkinson, ... Pathophysiology: ... #neurology #posture
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 Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
- Atypical Clinical ... ophthalmoplegia), systemic signs ... sarcoid or other CNS ... inflammatory cause ... ) • EMG/NCS (rare
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
impairment, Mood disorder ... Signs and symptoms ... Radiographic findings (eg ... Laboratory findings (eg ... VEP’s: EEG of visual
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... Cardiac, pulmonary etc ... ) • CNS -> PNS ... Lack of UMN/LMN signs ... electromyographic (EMG
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
risk factors (eg ... hypertension (eg ... 109 mm Hg) with clinical ... hypertension (eg ... Neurologic disorders
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