18 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... hydration - Hyperkalemia ... unless worrisome EKG
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
risk factors (eg ... hypertension (eg ... 109 mm Hg) with clinical ... hypertension (eg ... renal bruit or signs
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... brainstem syndromes (e.g ... AQP4-lgG disease; e.g ... Manifestations #diagnosis #neurology ... #symptoms #signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... hyperphosphatemia, hypercalcemia ... renal failure Clinical ... of diagnosis (e.g ... Diagnosis #Management #Signs
Evaluation and Management of Hypokalemia

Hypokalemia is often asymptomatic. Evaluation begins with a search for warning signs
search for warning signs ... or symptoms warranting ... electrocardiography (ECG ... Most cases of hypokalemia-induced ... #Evaluation #Algorithm
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Pathogenesis and clinical ... to produce all classes ... /Symptoms/Findings ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... fasciculations Common Symptoms ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
may precede the neurologic ... Blood transfusion, Hypercalcemia ... Etiology: • Pathophysiology ... Neurological symptoms ... • EEG: With persistent
Pseudohyperkalemia vs Reverse Hyperkalemia

Pseudohyperkalemia and reverse pseudohyperkalemia are both conditions where potassium levels appear falsely elevated.

Pseudohyperkalemia:
This
especially extreme, e.g ... • No clinical ... signs of hyperkalemia ... potassium • ECG ... no changes in ECG