13 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Liver disease, Etc ... IgM associated lymphoma ... disease, Malignant lymphoma ... differential #diagnosis #hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
(e.g. ... Sickled red cells ... Bite cells: G6PD ... Smear #Analysis #hematology ... interpretation #clinical
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g ... Autoimmune diseases • Clinical ... Autoimmune diseases (e.g ... Malignancies (eg ... #differential #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
the non-Hodgkin lymphoma ... Orange or Hep C Clinical ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... . lupus, CLL, lymphoma ... (usually IgM) (e.g ... . sickle cell disease ... differential #diagnosis #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... non-specific red cell ... polychromatophilic cells ... count, D-dimer, egg ... #Hematology #Pathology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Mean corpuscular (cell ... Red cell distribution ... of substrate (e.g ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
- Clinical Presentation ... Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full ... classification #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Patients with Hodgkin Lymphoma ... antithymocyte globulin, etc ... Hematopoietic stem cell ... HLA-selected products (e.g ... #Indications #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Still disease, dermatomyositis ... • Malignancy (e.g ... Endocrine disorders (e.g ... lymphopenia, low PLT • Anemia