26 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... #Rheumatology # ... diagnosis #management
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
(e.g., long QT ... syndrome, ARVC) ... Digoxin toxicity Symptoms ... 300 = NSVT EKG ... #differential #cardiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... renal failure Clinical ... are not caused ... of diagnosis (e.g ... Sarcoidosis #Diagnosis #Management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Clinical Manifestations ... unit activity on EMG ... of diazepam • EMG ... EMG Studies:
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... : • Clinical triad ... tissue disorder (e.g ... classification #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... them, but urgent rheumatology ... #Diagnosis #Management