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diagnosis hematology reactions transfusion activation anemia bloodbank cerebritis cns cryofibrinogenemia dermatology erythematosus indications irradiated irradiation lupus macrophage mas neurology oncology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
disorders (DiGeorge Syndrome ... receiving HLA-selected products ... (e.g., HLA-matched ... #Indications #Hematology ... #BloodBank #Management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Anemia Clinical ... result from low blood ... Anemia #oncology #hematology ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... due to marrow aplasia ... Blood products contain ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Fibrin degradation products ... #Diagnosis #Management ... #Hematology #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... due to marrow aplasia ... Blood products contain ... #diagnosis #management ... #hematology #reactions
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
of fibrin split products ... which can plug blood ... cryoglobulin (CG ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... Diagnosis: • A clinical ... Tetracyclines etc ... #Rheumatology # ... diagnosis #management
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