17 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Summary • Epidemiology ... 40, F:M 9:1 • Clinical ... #Management #Summary ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... permeability Diagnosis ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... #management #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... SJIA], systemic lupus ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... #management #treatment ... #summary #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Chronic B-cell activation ... #Rheumatology
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
hyponatremia, AKI, etc ... esp in work-up/management ... note, discharge summary ... will also get an EKG ... Pearls #Checklist #diagnosis
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... Syndrome: • Clinical ... Labs/Diagnosis: ... . systemic lupus ... classification #rheumatology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Cardiomyopathy - Summary ... Differential Diagnosis ... support for patients clinically ... teratogenic GDMT meds ... Cardiomyopathy #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... : • A clinical ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
and Management ... Summary Epidemiology ... Clinical Manifestations ... autoantibodies - TPO, TTG, etc ... #Management #treatment