7 results
Torsades de Pointes 
•Precipitated by drugs that prolong the QT interval 
•Class IA antidysrhythmics (procainamide, quinidine)
that prolong the QT ... interval •Class ... quinidine) •Class ... IC antidysrhythmics ... TorsadesDePointes #Diagnosis #Cardiology
Class I Antiarrhythmics and their Key Pharmacologic Properties

Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer")
Class IB
Class I Antiarrhythmics ... Properties Class ... Mayo, Pickle") Class ... results in prolonged QT ... Agents #Cardiology
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Classification Class ... Widens QRS complex Class ... potential • Prolongs QT ... interval Class ... #cardiology #pharmacology
Torsades de Pointes
• "Twisting of the pointes" 
• QRS axis swings from positive to negative direction
that prolong the QT ... interval Class ... quridine) Class ... TorsadesDePointes #Diagnosis #Cardiology ... #ECG #EKG
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
No pharmacologic ... (Haldol) - No pharmacologic ... SE: prolonged QTC ... #CriticalCare # ... diagnosis #management
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
wort - Increases QT ... potential arrhythmias Class ... wort - Increases QT ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
Checklist for Treatment of Delirium in the ICU 

Remove causative factors 
 - 
Exclude hypoglycemia if
Delirium in the ICU ... c deliriogenic meds ... sleeping, administer pharmacologic ... Delirium #Checklist #Management ... #CriticalCare