10 results
Torsades de Pointes 
•Precipitated by drugs that prolong the QT interval 
•Class IA antidysrhythmics (procainamide, quinidine)
that prolong the QT ... interval •Class ... quinidine) •Class ... IC antidysrhythmics ... TorsadesDePointes #Diagnosis #Cardiology
Class I Antiarrhythmics and their Key Pharmacologic Properties

Class IA = Quinidine, Procainamide, Disopyramide ("Quarter PounDer")
Class IB
Class I Antiarrhythmics ... Properties Class ... Mayo, Pickle") Class ... results in prolonged QT ... Agents #Cardiology
Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 • Slows depolarization
Classification Class ... Widens QRS complex Class ... potential • Prolongs QT ... interval Class ... #cardiology #pharmacology
Torsades de Pointes
• "Twisting of the pointes" 
• QRS axis swings from positive to negative direction
that prolong the QT ... interval Class ... quridine) Class ... TorsadesDePointes #Diagnosis #Cardiology ... #ECG #EKG
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
you need a non-OTC ... SE: prolonged QTC ... SE: prolonged QTC ... #CriticalCare # ... diagnosis #management
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
common in OR; in MICU ... of shock, HOCM, etc ... Vasopressors #Inotropes #management ... #criticalcare # ... comparison #table #pharmacology
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products
Angiotensin-Converting Enzyme Inhibitors (ACEIs)
 • Night-blooming
Interactions With OTC ... wort - Increases QT ... potential arrhythmias Class ... wort - Increases QT ... #Interactions #OTC
Checklist for Treatment of Delirium in the ICU 

Remove causative factors 
 - 
Exclude hypoglycemia if
Delirium in the ICU ... c deliriogenic meds ... sleeping, administer pharmacologic ... Delirium #Checklist #Management ... #CriticalCare
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
Admitting in the ICU ... hyponatremia, AKI, etc ... esp in work-up/management ... will also get an EKG ... diagnosis #workup #criticalcare
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
Consider known drug causes ... (eg. remifentanil ... , digoxin etc) ... Checklist #Diagnosis #Management ... #Workup #Cardiology