16 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
rupture, VSD, etc ... pharmacology ... inopressors #diagnosis ... #management #comparison ... #table
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
is not desired (e.g ... Bradyarrhythmias, Some cases ... Vasopressors #Inotropes #comparison ... #table #pharmacology ... #criticalcare
Vasopressors and Inotropes
 • Norepinephrine - Levophed - "Levo" - Generally thought of as the first
pressor added in shock ... , HOCM, etc ... Inotropes #management #criticalcare ... #summary #comparison ... #table #pharmacology
Shock - Differential Diagnosis Framework
MAP = CO x SVR
Hypovolemic (↓ Intravascular volume):
 • Hemorrhage, dehydration due
Shock - Differential ... findings based on cause ... adrenal crisis, drugs ... #table #comparison ... #criticalcare
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... for alternative causes ... Liver #Injury #Diagnosis ... #Algorithm #hepatology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
set of symptoms) caused ... barbituates, “Z-drugs ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Algorithm Endocrine ... Myasthenia Gravis Pharmacologic ... Abuse (e.g. ... #Algorithm #causes
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
antirheumatic drug ... hypoglycemia), QTc ... concomitant use of QTc ... medication have stock ... Hydroxychloroquine #HCQ #Pharmacology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... Drugs 5. ... , Hypotension, shock ... #rheumatology #comparison ... #table
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... hypoxemia/Sepsis etc ... circulation If drugs ... laboratory or diagnostic ... Alcohol • Type B2: Drugs