21 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... binds magnesium • Dosing ... and calcium • Dosing ... #pharmacology #table ... #comparison #binders
Hyperkalemia shortens repolarization; changes in the T wave provide the earliest clues to hyperpotassemia.
 - At
Hyperkalemia shortens ... repolarization causes ... prolonged PR and QT ... #EKG #ECG #Changes ... #Progression #Table
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
with caution - e.g ... #pharmacology #comparison ... #treatment #medications ... #dosing #drugs ... #table #pharmacotherapy
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Management Summary Causes ... Herpes, Coxsackie, etc ... Treatment of underlying ... per day until stable ... Diagnosis #Management #causes
Inpatient Management of Opioid Use Disorder: Methadone vs Buprenorphine - Comparison Table

Some patients may decline buprenorphine
Buprenorphine - Comparison ... Table Some patients ... medication assisted treatment ... Dosing usually begins ... Buprenorphine #Comparison
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... heparinized tube) • ECG ... only if no clear cause ... Elimination (see Table ... Redistribution Treatments
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Herpes, Coxsackie etc ... per day until stable ... Dialysis for severe hyperkalemia ... Management #Summary #causes ... #treatment
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
Causes of Hypokalemia ... plasma insulin (treatment ... laxative, enema abuse ... chloroquine, steroids, etc ... #Causes #differential
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... Consider known drug causes ... (eg. remifentanil ... , digoxin etc) ... myocardial infarction, hyperkalaemia
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Drugs that prolong QT ... Congenital long QT ... Hypomagnesemia • Hypokalemia ... Hypocalcemia (rarely) Treatment ... 1b (lidocaine)- case