33 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
rupture, VSD, etc ... hasankazmi01 #Vasopressors ... inopressors #diagnosis ... #management #comparison ... #table
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Resistance, Main Uses ... #Properties #Table ... #Pharmacology # ... Effect #Management #Comparison
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
with caution - e.g ... #pharmacology #comparison ... #treatment #medications ... #dosing #drugs ... #table #pharmacotherapy
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
dronedarone, dofetilide Vasopressors ... #Medications #Causes ... #differential #diagnosis ... #pharmacology # ... table
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
Common Vasopressors ... Bradyarrhythmias, Some cases ... Cardiac ischemia #Vasopressors ... #Inotropes #comparison ... #table #pharmacology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
set of symptoms) caused ... barbituates, “Z-drugs ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... DILI) - Stepwise Diagnosis ... /HDS treatments ... for alternative causes ... Liver #Injury #Diagnosis
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
prophylaxis and treatment ... tinnitus) and may cause ... It also can cause ... hypoglycemia), QTc ... Hydroxychloroquine #HCQ #Pharmacology
Hypotension - Guidelines for Crises in Anaesthesia

Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
anticholinergic drug ... Consider giving vasopressor ... and positioning (e.g ... could have made a drug ... Intraoperative #Checklist #Diagnosis
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... : Drugs: Ecstasy ... #Hyperthermia #comparison ... #diagnosis #management ... #treatment