35 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Diagnosis - Based ... Signs and symptoms ... patients with clinically ... stimulation Clinical
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
- Differential Diagnosis ... Algorithm Pre-Hepatic ... Sepsis • Drugs (e.g ... Cholangiocarcinoma • Primary Sclerosing ... #Algorithm #Causes
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Depression • Multiple Sclerosis ... Chronic Fatigue Syndrome ... #Algorithm #causes
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... #MSK #pathophysiology ... #diagnosis #symptoms ... #signs
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... for alternative causes ... cholangitis, Primary sclerosing ... #Algorithm #hepatology
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
illness What: Key signs ... and symptoms that ... define the clinical ... syndrome - Does ... #History #HPI #Diagnosis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
renal failure Clinical ... are not caused ... (e.g. incidental ... anterior/posterior MSK ... #Management #Signs
Restrictive Cardiomyopathy - Diagnosis and Causes
Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema)
Physical
and Causes Clinical ... ↑ "Right Sided-Symptoms ... Hyper-eosinophilc Syndrome ... Cardiomyopathy, Systemic Sclerosis ... #cardiology #algorithm
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology