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Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology

#Major #Syndromes #Nephrology #Diagnosis #Workup
Defining Major Syndromes ... #Major #Syndromes ... #Nephrology #Diagnosis ... #Workup #Differential ... #Table
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Aldosterone: Liddle's Syndrome ... SAME, Cushing Syndrome ... diuretics, Bartter syndrome ... , Gitelman syndrom ... #Algorithm #causes
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... Nephritic syndrome—due ... Nephrotic yndrome—podocyte ... Nephritic #Nephrotic #Syndromes ... #Diagnosis
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
polyneuropathy (e.g ... Guillain-Barré syndrome ... Hyperthyroidism, Serotonin syndrome ... #differential #diagnosis ... #table #neurology
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
Gap Metabolic Acidosis ... - Differential Diagnosis ... with short bowel syndrome ... anti-freeze, varnish, etc ... salicylate toxicity causes
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Renal tubular acidosis ... Diuretics, Bartter's syndrome ... , Gitelman's syndrome ... acid, Liddle's syndrome ... • Cushing's syndrome
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
renal Mg wasting syndromes ... - Gitelman syndrome ... - Hungry bones syndrome ... Low #Magnesium #Table ... #Workup #hypomg
Proposed Algorithm for Diagnosing Sarcoidosis
Highly suggestive Clinicoradiological Findings → Clinical diagnosis (without biopsy) e.g. Löfgren's syndrome
Suggestive
without biopsy) e.g ... Löfgren's syndrome ... and/or cytology (e.g ... of alternative causes ... #Workup
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm
Insufficient Sleep
 • Poor Sleep Hygiene
 • Insomnia
Causes of Excessive ... Shift Work) Sleep ... Restless Legs Syndrome ... Hypoventilation Syndrome ... Disorders • Neurologic
Workup for Hyperphosphatemia - Differential Diagnosis Framework
Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
Workup for Hyperphosphatemia ... - Differential Diagnosis ... Rhabdomyolysis, Tumor lysis syndrome ... Shift: • Lactic acidosis ... #phosphate #nephrology