31 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
: Is the PT or APTT ... K Antagonists, Heparin ... to identify the cause ... #prolonged #diagnosis ... #hematology #evaluation
Heparin Induced Thrombocytopenia (HIT) - Likelihood, Diagnosis and Management
 - HIT Suspected
 - Calculate 4T Score
Heparin Induced ... - Likelihood, Diagnosis ... - Start/Stop Heparin ... Results #HIT #Heparin ... #Management #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... deficiency • Reduced ... #hematology #coagulation
Heparin-Induced Thrombocytopenia (HIT) Evaluation Algorithm

- Dr. Josh Farkas @PulmCrit

#4TScore #HITT #Algorithm #HeparinInduced #Thrombocytopenia #Diagnosis #Criteria #Hematology
Heparin-Induced ... Thrombocytopenia #Diagnosis ... #Criteria #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
unfractionated heparin ... e.g. heparin ... thrombin inhibitors, heparin ... #diagnosis #differential ... #hematology #coagulation
Approach to suspected Heparin-Induced Thrombocytopenia (HIT)

 • Suspected HIT Algorithm
 • "4 T's" clinical probability score:
Approach to suspected Heparin-Induced ... NephPrasad #Heparin ... #Induced #Thrombocytopenia ... #HIT #hematology ... #diagnosis #4Ts
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
- Differential Diagnosis ... hemoglobin/hemosiderin, Hepatic ... antiglobulin test, PT/aPTT ... hemosiderin • PT/aPTT ... Management #Algorithm #hematology
4-T Score for the Likelihood of Heparin Induced Thrombocytopenia
 - Thrombocytopenia - Compare the highest platelet
count
Likelihood of Heparin ... Other potential cause ... #4TScore #HIT #Heparin ... #Likelihood #Diagnosis ... #Hematology
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
4T Score for Heparin-Induced ... avoid checking heparin-PF4 ... 10%) - Stop heparin ... Thrombocytopenia #Diagnosis ... #Criteria #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... - Differential Diagnosis ... Hepatic, Portal, ... #Differential #Diagnosis ... #Hematology