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differential obstetrics pregnancy thrombocytopenia algorithm comparison hellp management obgyn ttphus biliary blood cell cholangitis cirrhosis dili disorders druginduced fatty injury
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
of Pregnancy (AFLP ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Algorithm #Causes
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... = nonspecific (nausea ... develops (DIC, ascites ... iMedEducation #AFLP ... Pregnancy #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... gastric bypass), LFT ... #Causes #Workup ... #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... for alternative causes ... . ascites), Chronic ... #Injury #Diagnosis ... #Algorithm #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
Ascites - Diagnostic ... The most common causes ... (e.g. cirrhosis ... #workup #Differential ... #Diagnosis #hepatology
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
child * Severe cases ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... cholestasis → Cirrhosis/Liver ... obstruction • ALP ... or higher • Liver ... #workup #hepatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
red bone marrow, e.g ... appearance Favored Sites ... common - GI tract, liver ... Diagnosis? ... #Workup #Hematology
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