14 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Artifactually Prolonged ... K Antagonists, Heparin ... identify the cause of Prolonged ... #prolonged #diagnosis ... #hematology #evaluation
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
unfractionated heparin ... . heparin contamination ... thrombin inhibitors, heparin ... #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... . heparin contamination ... thrombin inhibitors, heparin ... #diagnosis #differential ... #hematology #coagulation
Appearance of Liver Lesions on Computed Tomography (CT) - Arterial Phase, Portal Venous Phase and Delayed
Appearance of Liver ... Liver #Lesions #Hepatic ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Appearance of Liver ... Liver #Lesions #Hepatic ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... • Acute DIC - Septic ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Thrombocytopenia • Prolonged ... 100mg/dL) - Heparin ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... treatment #management #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... is prolonged, but ... mixing study (aPTT ... hemophilia type (e.g ... Management #treatment #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... liver disease, Hepatic ... presentation: Hepatic ... Liver #Injury #Diagnosis ... #Algorithm #hepatology
Appearance of Liver Lesions on Contrast Enhanced Ultrasound - Early arterial, Grayscale phase, Late arterial phase,
Appearance of Liver ... Liver #Lesions #Hepatic ... #differential #diagnosis ... #comparison #table ... #appearance #hepatology