13 results
Heparin-Induced Thrombocytopenia (HIT) Evaluation Algorithm

- Dr. Josh Farkas @PulmCrit

#4TScore #HITT #Algorithm #HeparinInduced #Thrombocytopenia #Diagnosis #Criteria #Hematology
Heparin-Induced ... Thrombocytopenia ... HeparinInduced #Thrombocytopenia ... #Diagnosis #Criteria ... #Hematology
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
- Differential Diagnosis ... Table • Thrombotic ... Thrombocytopenic ... TMA - Drug-induced ... Microangiopathy #TMA #hematology
4T Score for Heparin-Induced Thrombocytopenia

Interpretation of the 4T score:
0-3 points:  Low probability (<<1%)
  -
Score for Heparin-Induced ... Thrombocytopenia ... HeparinInduced #Thrombocytopenia ... #Diagnosis #Criteria ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Causes: - Drug induced ... fever • Drug reactions ... #hematology #rheumatology ... #nonpalpable #dermatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... Other: Transfusion reaction ... #differential #diagnosis ... #hematology #anemia
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... : ARDS Berlin Criteria ... #Transfusion #Reactions ... #hematology #diagnosis ... #comparison #table
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Mechanical valve induced ... , Etc. ... #differential #diagnosis ... #hematology #microscopy
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #Transfusions #diagnosis ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Sepsis • Drug-induced ... leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology