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blood product syndrome transfusion activation anemia arteritis causes comparison dermatology differential extravascular gca giantcell hemeonc hemolysis hemolytic hemophagocytic hlh intravascular
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... Other: Transfusion reaction ... #differential #diagnosis ... #hematology #anemia
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... : ARDS Berlin Criteria ... #Transfusion #Reactions ... #hematology #diagnosis ... #comparison #table
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #Transfusions #diagnosis ... #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
antiinflammatory properties e.g ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... E.g. 80 yo ESR cutoff ... vision changes, etc ... them, but urgent rheumatology ... #Management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Cytopenias (anemia, thrombocytopenia ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... #Management #Hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
standing for: - Thrombocytopenia ... mesothelioma, etc ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
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