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differential algorithm causes management rheumatology anemia oncology atlas blood comparison hemolytic nomenclature platelet product syndrome activation basics bloodcell bruising cell
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... - History of bleeding ... #Causes #Workup ... #hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... Rare • Drugs (e.g ... Algorithm #Causes #Hematology
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
common inherited bleeding ... disorder Clinical ... platelet count (mild thrombocytopenia ... VonWillebrand #Disease #Diagnosis ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... fever • Drug reactions ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... allergy, drug reaction ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... Other: Transfusion reaction ... lymphoproliferative disorders ... #hematology #anemia
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malignancy, Autoimmune disorders ... (e.g. ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... #Algorithm #workup ... #hematology #testing
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... Defects #comparison #table ... #differential #diagnosis ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... coagulopathy & ↑bleeding ... #Transfusion #diagnosis ... #management #hematology
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