32 results
Shock and Vasoactive Drugs 
1) Determine type and etiology of shock
 • Distributive: Sepsis, Anaphylaxis, Neurogenic
rupture, VSD, etc ... Pericardial tamponade, Pulmonary ... inopressors #diagnosis ... #management #comparison ... #table
PDE5 inhibitors are usually the drugs of first choice for erectile dysfunction.

PDE5 inhibitors enhance an erection that is
are usually the drugs ... with caution - e.g ... #pharmacology #comparison ... #treatment #medications ... #table #pharmacotherapy
Vasopressors Table 
Rough properties by Target Receptor, Heart Rate/Inotropy, Systemic Vascular Resistance, Cardiac Output, Blood Pressure,
Vasopressors Table ... Blood Pressure, Pulmonary ... Resistance, Main Uses ... #Pharmacology # ... Effect #Management #Comparison
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
set of symptoms) caused ... barbituates, “Z-drugs ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
- Differential Diagnosis ... hemorrhage) - Pulmonary ... exacerbation) - Drugs ... #Differential #Diagnosis ... #Table #Causes
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... DILI) - Stepwise Diagnosis ... /HDS treatments ... for alternative causes ... Liver #Injury #Diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... - Differential Diagnosis ... Chronic Obstructive Pulmonary ... Myasthenia Gravis Pharmacologic ... Abuse (e.g.
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
antirheumatic drug ... prophylaxis and treatment ... hypoglycemia), QTc ... concomitant use of QTc ... Hydroxychloroquine #HCQ #Pharmacology
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... : Drugs: Ecstasy ... #Hyperthermia #comparison ... #diagnosis #management ... #treatment
Common Vasopressors and Inotropes
Norepinephrine (NE)
 - Indication: Distributive shock (1st line for septic shock), Cardiogenic shock
is not desired (e.g ... Bradyarrhythmias, Some cases ... Vasopressors #Inotropes #comparison ... #table #pharmacology ... #criticalcare