19 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... cases: INR/PT, aPTT ... function test, ANA (e.g ... #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
to HDS, drugs, OTC ... of information (e.g ... Hepatic vascular disorder ... (e.g. ascites), ... Diagnosis #Algorithm #hepatology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Approach to Anemia - Differential ... aciduria, Drugs (e.g ... Non-megaloblastic: Liver ... #Algorithm #Differential ... #Diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... ) - Differential ... Chronic Disease (e.g ... Renal Disease, Liver ... Algorithm #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... ) - Differential ... Increased Requirement (e.g ... • Small Bowel Disorder ... Algorithm #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... inhibitory drugs e.g ... Causes #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Pre-analytical cause (e.g ... inhibitory drugs (e.g ... specific inhibitor (e.g ... • Reduced liver ... #hematology #coagulation
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
) - Differential ... Iron Deficiency (Eg ... Other • e.g ... HgbE, HgbC, etc. ... Algorithm #Causes #Hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... ) • Advanced Liver ... (e.g. ... comparison #diagnosis #hematology