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diagnosis differential algorithm treatment hematology neurology classification criticalcare pharmacology rheumatology bradycardia checklist chronic comparison dermatology elevation endocarditis icu inflammatory rhabdomyolysis
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
, hemolytic anemias ... , drug reactions ... , certain drugs, ... infections, infectious ... #differential #causes
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... methotrexate) • Drugs ... Non-lmmune: • HELLP Syndrome ... Vasculitis • Infection
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... ) - Drugs ( ... Extravascular #Causes
Priapism Secondary Causes: Medications- intracavernosal injections, anticoagulants, PDE5 inhibitors, alpha blockers, methylphenidate, cocaine Any hyperviscosity syndrome (SCD, leukemia,
Secondary Causes ... : Medications- ... hyperviscosity syndrome ... leukemia, myeloma, etc ... Priapism #Diagnosis #Management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... - Cytotoxic drugs ... - Antithyroid medications ... Idiopathic • Infections ... hematology #diagnosis #management
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins. There are 5
toxidrome is a syndrome ... set of symptoms) caused ... by specific medications ... barbituates, “Z-drugs ... Toxidromes #Comparison #Table
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... vasoconstriction syndrome ... Toxic: Alcohol, Medication ... , Recreational drugs ... brain injury • Infectious
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... duration), Several medications ... , Hidden OTC and ... for alternative causes ... Hepatocellular: Viral infections
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Hematologic • Anemia ... • Malignancy Infectious ... Abuse (e.g. ... Chronic Fatigue Syndrome
Causes of Pericardial Effusion - Differential Diagnosis Infectious: • Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus • Bacterial: Mycobacterium
Causes of Pericardial ... , Candida Non-Infectious ... • Metabolic: Uremia ... Dissection, Idiopathic, Drug-related ... #cardiology
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