48 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... Non-lmmune: • HELLP Syndrome ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... ) - HELLP syndrome ... infection) - Drugs ... #hematology #anemia
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... duration), Several medications ... /HDS treatments ... for alternative causes ... #Algorithm #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... #Management #treatment ... #hematology #oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... - Differential Diagnosis ... Blood Smear • Drugs ... Myelodysplastic Syndromes ... #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... - Antithyroid medications ... Treatment: ... #oncology #hematology ... #diagnosis #management
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
toxidrome is a syndrome ... set of symptoms) caused ... by specific medications ... barbituates, “Z-drugs ... antihistamines #Diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Anemia • ... Abuse (e.g. ... Chronic Fatigue Syndrome
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
halt nail growth (e.g ... Discoloration • Medications ... • Nephrotic syndrome ... #Differential #Diagnosis ... #Algorithm #causes
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... : Drugs: Ecstasy ... ; Serotonin syndrome ... Hyperthermia #comparison #diagnosis ... #management #treatment