14 results
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
chemotherapy, etc ... associated with renal ... suspected • Hypercalcemia ... possible malignancy (e.g ... Electrophoresis #SPEP #Hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Herpes, Coxsackie, etc ... : • Triad of symptoms ... urine • Other symptoms ... per day until stable
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... Urine: UA, Urine protein ... recent DAN) • EMG ... or serologies + symptoms ... differential #diagnosis #management
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
IgM monoclonal protein ... constitutional symptoms ... damage, such as hyperCalcemia ... , Renal insufficiency ... #Significance #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... hydration - Hyperkalemia ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulin (CG ... Cryofibrinogenemia Symptoms ... thrombophlebitis, pulmonary ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... hyperphosphatemia, hypercalcemia ... , and possibly renal ... of diagnosis (e.g ... Pulmonary: dyspnea
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... Anaphylaxis, Acute Renal ... APML #diagnosis #management ... #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
. hematologic) ... pancreatitis, protein-losing ... APLA/LAC: • Renal ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vision changes, etc ... them, but urgent rheumatology ... absence of visual symptoms ... Temporal #Signs #Symptoms ... #Diagnosis #Management