13 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... . lupus, CLL, lymphoma ... infection) - Drugs ... Extravascular #Causes #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Liver disease, Etc ... disorders, Oxidative drugs ... RBC #Morphology #differential ... #diagnosis #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... duration), Several medications ... /HDS treatments ... Liver #Injury #Diagnosis ... #Algorithm #hepatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
asthma, allergy, drug ... glucocorticoid treatment ... signs or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... lymphopenia, low PLT • Anemia ... extremities Drug ... • Antihistone: Drug ... activation and/or medications
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Lupus Erythematosus ... for 1 year of treatment ... Erythematosus #medications ... #risk #differential ... #diagnosis #rheumatology
Causes of Acute Pericarditis:

Infectious;

Viral: 
Adenovirus 
Coxsackie virus A and B 
Echovirus 
Epstein-Barr virus 
Hepatitis 
Human immunodeficiency
- related Medication ... induced (select drugs ... syndrome Systemic lupus ... #Pericarditis #Differential ... #Diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SJIA], systemic lupus ... ) • Sepsis • Drug-induced ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... hypoxemia/Sepsis etc ... circulation If drugs ... 30mmHg) - Severe anemia ... - HIV/HAART medications
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... vision changes, etc ... systemic complaints- anemia ... of the steroid treatment ... Treatment of GCA