12 results
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Rheumatoid Arthritis ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... colored compounds (e.g ... heme, bilirubin, etc ... #Urine #Microscopy ... #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... of information (e.g ... non-essential drug/HDS treatments ... for alternative causes ... vascular disorder (e.g
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... vision changes, etc ... Treatment of GCA
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Lumbar Puncture, EEG ... Treatment: ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
syndrome, rheumatoid arthritis ... myasthenia Diagnosis ... Serologic and EMG ... Myasthenia #Gravis #diagnosis ... #management #neurology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Discontinuation of causal ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Labs/Diagnosis: ... vasculitis - GPA, EGPA, microscopic ... tissue disorder (e.g
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
polarized light microscopy ... inflammatory disease (e.g ... Chemistry profile (e.g ... (to support a diagnosis ... laboratory #workup #diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... Rule out other causes ... and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc