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diagnosis management blood differential product transfusion algorithm antinxp2dm arteritis comparison dermatomyositis disorders eosinophil eosinophilia gca giantcell mds myelodysplasia myelodysplastic neutropenia
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
allergy, drug reaction ... glucocorticoid treatment ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... without other cause ... : 33% • Treatment ... #hematology #diagnosis ... #comparison #table
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... Causes purpura & ... TRALI): Leading cause ... infections with skin ... diagnosis #management #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Constitutional disorders, eg ... Idiosyncratic drug reactions ... Idiosyncratic drug reactions-most ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... Causes purpura & ... infections with skin ... diagnosis #management #hematology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
Muscle atrophy may cause ... positive patients Treatment ... three days #AntiNXP2DM ... diagnosis #management #rheumatology ... #dermatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vision changes, etc ... required due to skip ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... Out Secondary Causes ... Workup: • Complete ... Syndromes #diagnosis #hematology
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