16 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... glucocorticoid treatment ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... Hypocellular/Hypoplastic MDS ... anemia Treatment ... Anemia #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... Infection exposure (l MD ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
toxic aetiology: Skin ... of information (e.g ... treatments Search ... for alternative causes ... Diagnosis #Algorithm #hepatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... hemophilia type (e.g ... by a hemophilia treatment ... Avoid meds that ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Pure red cell aplasia ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... • Anemia • Aplastic ... Workup: • Complete ... Syndromes #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... hypertension and/or drug treatment ... Constitutional disorders, eg ... white blood cell aplasia ... #hematology