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diagnosis management oncology blood differential product transfusion algorithm anemia arteritis chronic cll comparison disorders eosinophil eosinophilia gca giantcell leukemia lymphocytic
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
allergy, drug reaction ... glucocorticoid treatment ... signs or symptoms (eg ... , skin or esophageal ... Differential #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Headaches • Pale skin ... and petechiae Causes ... anemia Treatment ... Anemia #oncology #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... without other cause ... : 33% • Treatment ... #hematology #diagnosis ... #comparison #table
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Constitutional disorders, eg ... Idiosyncratic drug reactions ... white blood cell aplasia ... #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... Causes purpura & ... due to marrow aplasia ... infections with skin ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... due to marrow aplasia ... infections with skin ... diagnosis #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... and lower jaw Treatment ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... diagnosis #management #Dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... Pure red cell aplasia ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... • Anemia • Aplastic ... Workup: • Complete ... Syndromes #diagnosis #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
vision changes, etc ... required due to skip ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology
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