43 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... suspect underlying hematologic ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
immunodeficiency disorders ... (DiGeorge Syndrome ... Immunodeficiency Disorder ... HLA-selected products (e.g ... #Indications #Hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... (e.g. lymphoma, ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... • Peripheral blood ... glucocorticoid treatment ... signs or symptoms (eg ... Differential #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... plateletcount), peripheral blood ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Causes of Thrombocytosis ... Chronic inflammatory disorders ... (e.g. autoimmune ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Algorithm Normal Blood ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... lymphoproliferative disorders ... differential #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
hypertension and/or drug treatment ... , eg, cyclic neutropenia ... , Kostmann syndrome ... including white blood ... #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Causes of Anemia ... Causes: Chronic ... Blood Loss, Occult ... HgbE, HgbC, etc. ... #Hematology