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diagnosis differential management oncology algorithm anemia causes chronic hemolytic leukemia lymphocytic platelet rbc rheumatology atlas blood bloodbank bloodcell cell classification
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... function test, ANA (e.g ... not required in all ... Diagnosis #Causes #Workup ... #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoproliferative disorders ... Neutropenia, anemia, thrombocytopenia ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
microangiopathy: Thrombotic thrombocytopenic ... . lupus, CLL, lymphoma ... lymphoproliferative disorders ... . sickle cell disease ... differential #diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... evaluation or workup ... glucocorticoid treatment ... signs or symptoms (eg ... Differential #diagnosis #hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
immunodeficiency disorders ... Immunodeficiency Disorder ... Hematopoietic stem cell ... HLA-selected products (e.g ... #Indications #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... leukemia in adults • Disorder ... Symptoms of anemia or thrombocytopenia ... with anemia or thrombocytopenia ... Leukemia #oncology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... Schistocytes, thrombocytopenia ... Consider RBC membrane disorder ... Diagnosis #Algorithm #workup ... #hematology #testing
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Liver disease, Etc ... valve induced, Etc ... Unstable hemoglobin disorders ... differential #diagnosis #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
receptor] • Thrombocytopenia ... MYH9-Related Disorder ... structure and cell ... Defects #comparison #table ... differential #diagnosis #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Mean corpuscular (cell ... (BM) ablative disorders ... of substrate (e.g ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
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