9 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... Special cases (e.g ... #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
DAAs #Antivirals #table ... #treatment #hcv ... #medications #infectiousdisease ... #hepatology #HepC ... HepatitisC #Management #Pharmacology
Drugs Used for the Treatment of COVID-19 Infection

** Editor Note (from ophthalmology MD input) - Hydroxychloroquine/chloroquine
ophthalmology MD input) - Hydroxychloroquine ... HCQ treatment would ... or detachment, etc ... #Pharmacology # ... Table #Management
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Hydroxychloroquine ... and Benefits in Lupus ... - Prolonged QTc ... #hcq #Risks #Benefits ... #Lupus #pharmacology
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
Known to Prolong QTc ... mefloquine, quinine, hydroxychloroquine ... #differential #diagnosis ... #pharmacology # ... table
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
prophylaxis and treatment ... side effects (e.g ... hypoglycemia), QTc ... concomitant use of QTc ... #HCQ #Pharmacology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... duration), Several medications ... non-essential drug/HDS treatments ... infections (HAV, HBV, HCV ... #Algorithm #hepatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
causal drug +++, Hydroxychloroquine ... life-threatening • Treatment ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Induced Systemic Lupus ... for 1 year of treatment ... #drugs #pharmacology ... #differential #diagnosis ... #rheumatology