18 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
process whereas secondary ... primary biliary cirrhosis ... (PBC), or with ... #Pathophysiology ... #Diagnosis #Signs
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary Cirrhosis ... Pathophysiology ... Signs and Symptoms ... bile ducts Differential ... #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... Diagnosis Portal ... and hepatorenal syndrome ... #Diagnosis #causes ... #hepatology
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
procoagulopathy or secondary ... post-sinusoidal: Budd-Chiari syndrome ... portalhypertension #phtn #differential ... #diagnosis #causes ... #hepatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... Myelodysplastic syndrome ... Myelofibrosis (MF ... #hematology #secondary
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
Diagnosis • Physiological ... sludge), Mirizzi's syndrome ... pancreatitis, PSC ... (or secondary SC ... #diagnosis #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... , Evans Syndrome ... #Diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... hepatitis: < 1 • Cirrhosis ... #hepatology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Diagnosis Approach ... previously stable values ... hypertension and signs ... renal bruit or signs