15 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Diagnosis Algorithm ... ALP: - Enzymes ... Bone symptoms - Pain ... #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... + ULN ALT) / (alkaline ... Transaminitis #diagnosis #differential ... #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... ALP, alkaline phosphatase ... ; ALT, alanine aminotransferase ... #Hepatology #Liver ... #Enzymes #Differential
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Enzyme Elevation ... #diagnosis #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Cholestatic disease ... Bile Ducts • PSC
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
compared with alkaline ... disproportionate increase in alkaline ... HELLP, Celiac disease ... #Diagnosis #hepatology ... #algorithm #Transaminitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... of cholestatic disease ... disease: > 2 ... Enzyme Elevation ... chemistry #diagnosis #differential
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... enzymes, or family ... enzymes to rule ... disease. ... ALT, alanine aminotransferase
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
ALP enzyme- Discovered ... synthesized in: liver ... risk of joint pain ... Malnutrition • Wilson's disease ... Hyophosphatasia #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... Labs: • Alkaline ... obstruction • ALP ... or higher • Liver ... bile ducts Differential