8 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Algorithm for Transaminitis ... or AST > ALP): ... Cholestatic Pattern (ALP
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
elevation > Alk ... • R value = (ALT ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... of cholestatic disease ... disease: > 2 ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Bilirubin - +/- elevation ... Enzyme Elevation ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... • Drugs • AIH ... • Cholestatic disease ... Bile Ducts • PSC
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... #Diagnosis #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... hepatocellular pattern of liver ... been reported (eg AIH-PBC ... (rare) - IgG Elevation