16 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... • NAFLD • Cirrhosis ... Diagnosis #hepatology ... #transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... Burak @kwburak #LFTs
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... CMV), Alcoholic cirrhosis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... , Acute biliary ... Extrahepatic • Biliary ... #Injury #Differential ... Acute #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... • Alcoholic hepatitis ... Duct Stone • Biliary ... • Others #LFTs
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... congenital - Primary biliary ... Nonalcoholic fatty liver ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Diagnosis Chronic liver ... disease (cirrhosis ... or chronic hepatitis ... Failure, Pancreatic, Biliary ... #Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... HELLP, Celiac disease ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... /Liver failure ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... #Cirrhosis #PBC
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hepatomegaly - Differential ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly