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diagnosis hepatology algorithm causes lfts management pbc primary psc abnormal alkaline alp antibodies ascites associations autoantibodies biliary chemistry comparison diseases
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis ... Primary Sclerosing Cholangitis ... #psc #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
/Liver failure ... or higher • Liver ... bile ducts Differential ... #PBC #cholangitis ... diagnosis #workup #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Algorithm for Transaminitis ... Congenital, Others, Cirrhosis ... Algorithm #diagnosis #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
Primary Sclerosing Cholangitis ... • CHOLANGITIS ... • CIRRHOSIS - ... indications for liver ... management #summary #Hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... Primary biliary Cholangitis ... ALP #Elevation #Differential
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Primary Biliary Cirrhosis ... Algorithm #Causes #Hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites - Differential ... - Hepatic: • Cirrhosis ... • Infiltrative disease ... • Acute liver ... Primary biliary cholangitis
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... Primary biliary cirrhosis ... (PBC) Anticentromere ... Endomyseal antibody (EMA ... diagnosis #table #rheumatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Venoocclusive disease ... hepatitis: < 1 • Cirrhosis ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... #Diagnosis #hematology
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