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diagnosis algorithm hepatology elevation acidosis alp biliary causes cholangitis cirrhosis classification dili gap globulin hemolysis idiosyncratic induced injury lactate lactic
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... Cholestasis - Drugs ... Hepatic source: - Drugs
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypothyroid • Liver ... Disease • Alcohol ... • Drugs Matthew ... #differential # ... #workup
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... , PCH, Evans Syndrome ... , Liver Disease, ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... disease 6-9 mo ... Calculate R-Value ... Idiosyncratic #differential ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Labs: • Alkaline ... bile ducts Differential ... , Sarcoidosis, Drug-induced ... cholangitis #diagnosis #workup ... #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... presentations and disease ... circulation If drugs ... 30mmHg) - Severe anemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Sarcoidosis) • Liver ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential ... #diagnosis #hematology
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