10 results
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Values • pH: ... Diagnosis: Causes ... D-lactate (short bowel syndrome ... GBS, Myasthenia gravis ... restrictive lung disease
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
DIC, HELLP - Grafts ... , Valves, AS ... Drug-associated, PCH ... , Evans Syndrome ... #Diagnosis #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... Anti-TSHR - Graves ... Endomyseal antibody (EMA ... #diagnosis #table ... #rheumatology #
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Ab to AChR blocks ... life-threatening Differential ... myasthenia Diagnosis ... Serologic and EMG ... #diagnosis #management
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
Knee Effusions - Differential ... Diagnosis Framework ... Effusions: - Hematologic ... Ravi Singh @rav7ks ... #diagnosis #msk
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic ... vein thrombosis Hematologic ... Erythematosus #Diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... renal tubular acidosis ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Diagnosis #Management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Ravi Singh @rav7ks ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... to bolus these values ... presentations and disease ... - Compartment syndrome ... #Elevation #Differential
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Aldolase levels • EMG ... Anti-Synthetase Ab ... : • PBC, autoimmune ... #differential #