8 results
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... • Iatrogenic: DILI ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Injury (DILI) ... Calculate R-Value ... • Hepatocellular ... #differential # ... gastroenterology #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
abnormality vs bone Bili ... ≥ 2x ULN R Value ... ≥5: Hepatocellular ... injury >2 ... Transaminitis #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... ) • R > 5: Hepatocellular ... Check Acute viral hepatitis ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Diagnosis Hepatocellular ... Celiac Disease Hepatocellular ... #Injury #Differential ... Acute #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... 10x ULN), ↑Tbili/Dbili ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Pregnancy #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
- Typically hepatocellular ... pattern of liver ... injury, though ... reported (eg AIH-PBC ... #Hepatology
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
fibrosis score with values ... 4, fibrosis-4; HCC ... , hepatocellular ... algorithm #Referral #Management ... #Hepatology