14 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Intestine - Other causes ... Cholestasis - Drugs ... - Primary biliary ... Diagnosis #Algorithm #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
obstruction - Drug-Induced ... hepatitis - Wilson disease ... Hemochromatosis - Primary ... #Differential # ... Hepatology #Diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Liver Mass - Differential Diagnosis Algorithm
Cystic:
 • Benign 
     - Simple: Simple
Liver Mass - Differential ... Disease, Caroli's ... Malignant - primary ... Diagnosis #Algorithm #Causes ... #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... , Recreational Drugs ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Hepatitis • Drug ... Diagnosis #Algorithm #Causes ... #Hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... , PCH, Evans Syndrome ... , Liver Disease, ... #Diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... or higher • Liver ... bile ducts Differential ... , Sarcoidosis, Drug-induced ... diagnosis #workup #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
disease, decrease ... gastric bypass), LFT ... (liver disease) ... unclear, or if a primary ... #Workup #hematology