20 results
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
PCR 50% sensitive ... multiple lesions Infectious ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Generalized Weakness - Differential ... Resp/Heme: CHF, valves ... Polyneuropathy, ALS), NMJ disorder ... #Diagnosis #causes ... #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
CNS Infection in ... HIV / AIDS - Differential ... Suspect in movement disorders ... Demyelinating disease caused ... #Infections #differential
Alice in Wonderland Syndrome
What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
CNS: parietal ... (Many causes!) ... ) • Infection ( ... • Psychiatric disorders ... #differential
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
- Differential ... Thrombocytosis): • Acute infection ... Chronic inflammatory disorders ... (e.g. autoimmune ... Myelofibrosis (MF
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Causes of Extravascular ... Cold AIHA • Alloimmune ... circulation - Infections ... Cold AIHA • PCH ... Prosthetic heart valves
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoproliferative disorder ... Agglutinin Syndrome (CAS ... , autoimmune disorder ... CLL (older) • Autoimmune ... younger pts) Differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... pulmonary etc) • CNS ... • Inflammatory disorders ... necrotizing myopathy • Autoimmune
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
nervous system (CNS ... an underlying autoimmune ... Inflammatory causes ... optica spectrum disorder ... #inflammatory #differential
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... an underlying autoimmune ... Non-inflammatory causes ... noninflammatory #differential