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hematology hemolysis neurology acid acidbase agglutinin algorithm anemia bandemia base bloodgas causes cbc cold disease disorders erythematosus extravascular gravis hemolytic
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Membrane): - Autoimmune ... , PCH, Evans Syndrome ... #Diagnosis #hematology
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Values • pH: ... acidosis: - CNS ... #Summary #Nephrology ... #ABG #bloodgas ... #VBG #differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Diagnosis Algorithm ... Cold AIHA • Alloimmune ... Cold AIHA • PCH ... Prosthetic heart valves ... #Causes #Hematology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... pulmonary etc) • CNS ... necrotizing myopathy • Autoimmune ... #Diagnosis #neurology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... Viral infection, autoimmune ... CLL (older) • Autoimmune ... younger pts) Differential ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... rheumatologic diseases ... and CNS • Headache ... extremities Drug ... #Rheumatology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ab to AChR blocks ... life-threatening Differential ... variants of GBS ... Serologic and EMG ... precipitated by: Drugs
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Cell population has ... Corticosteroid use • Autoimmune ... appreciate the value ... science/article/abs ... #WBC #CBC #hematology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Anti-Synthetase Ab ... • Misdiagnosed as ... effects of the drug ... #differential #
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