10 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... Sophia_Hayes_MD #Liver #Injury ... #Differential # ... Acute #algorithm #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Chronic viral hepatitis ... cardiac muscle, kidneys ... #hepatitis #differential ... diagnosis #algorithm #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... muscle, liver, and kidney ... • Hemolytic Anemias ... - Prosthetic valves ... Dehydrogenase #Elevated #differential
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal

PRE-RENAL 
Impaired perfusion: 
•
Injury ( AKI ) ... • Inflammatory disease ... Urethral stricture/valves ... Postrenal #Failure #Differential ... #Nephrology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... of cholestatic disease ... Alcoholic liver disease ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Noninfectious hepatitis ... lymphopenia, low PLT • Anemia ... C4) • ds-DNA: Kidney ... induced SLE • Kidney
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Treatment: - Acute kidney ... injury with serum ... - Concomitant diseases ... HCV, DILI, HCC, ... Management #Algorithm #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
• Heavy chain disease ... HBV, EBV, VZV, hepatitis ... , PBC, PSC, Viral ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... presentations and disease ... liver or renal injury ... 30mmHg) - Severe anemia