13 results
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal ... Motor Nerves: ALS ... Poliomyelitis, Guillain-Barre ... Syndrome, Myasthenia Gravis ... #Causes #differential
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1-2 cases ... complete paralysis of all ... Treatment: • Plasmapheresis ... diagnosis #management #treatment ... #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Limb- proximal weakness ... life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG ... diagnosis #management #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Bacteremia, Sepsis • Kidneys ... Resp/Heme: CHF, valves ... Polyneuropathy, ALS ... Diagnosis #causes ... #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Differentials? ... And BMP Normal Values ... Neuromuscular weakness ... GBS, Myasthenia gravis ... Diagnosis #Summary #Nephrology
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... More likely to cause ... glucocorticoids - can cause ... #Myasthenia #Gravis ... diagnosis #management #neurology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
SIGNS: • Muscle weakness ... Hypotension • AMS ... unloading • Kidney ... metabolic acidosis ... Pathophysiology #Nephrology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT ... diagnosis #management #neurology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... www.ncbi.nlm.nih.gov/pmc ... to bolus these values ... before beginning treatment ... #Elevation #Differential
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping ... , nausea, paresthesias ... Antibiotics (Bactrim, PCN ... only if no clear cause ... #potassium #nephrology