17 results
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Resp/Heme: CHF, valves ... Polyneuropathy, ALS), NMJ disorder ... (Myasthenia, LEMS ... Diagnosis #causes ... #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... life-threatening Differential ... Serologic and EMG ... failure - Can be ... diagnosis #management #neurology
Causes of Proximal Muscle Weakness That May Mimic Inflammatory Myopathy
 • Central or peripheral neurologic disease
Causes of Proximal ... Muscle Weakness ... neurologic disease • Myasthenia ... mimics #diagnosis #differential ... #causes #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Non-neuromuscular disorder ... pulmonary etc) • CNS ... Postsynaptic: Myasthenia ... #Differential #
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
serologic, and EMG ... More likely to cause ... or respiratory weakness ... glucocorticoids - can cause ... diagnosis #management #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
And BMP Normal Values ... acidosis: - CNS ... Neuromuscular weakness ... (GBS, Myasthenia ... Diagnosis #Summary #Nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
PCR 50% sensitive ... nodules, may also see ... Lesions #Brain #differential ... #diagnosis #causes ... #radiology #neurology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... nervous system (CNS ... Inflammatory causes ... optica spectrum disorder ... #inflammatory #differential
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Suspect in movement disorders ... Demyelinating disease caused ... #Infections #differential ... InfectiousDiseases #Neurology
Guillain–Barré syndrome (GBS)
(aka: Landry–Guillain–Barré–Strohl syndrome:
	Most common cause of acute flaccid paralysis
	Rapidly progressive ascending paralysis & areflexia
	Autonomic
 Most common cause ... motor systems may be ... Differential diagnosis ... :  Myasthenia ... Multiple Sclerosis: CNS